what is proin for dogs used for

what is proin for dogs used for

What’s phenylpropanolamine?

Phenylpropanolamine (model names: Proin®, Propalin®, Cystolamine®, Uricon®, Uriflex-PT®) is a sympathomimetic remedy used to deal with urinary incontinence resulting from poor muscle tone within the urethral sphincter.

Its use in cats and canines at sure doses to deal with urinary incontinence is ‘off label’ or ‘additional label’. Many medicine are generally prescribed for off label use in veterinary drugs. In these cases, comply with your veterinarian’s instructions and cautions very rigorously as their instructions could also be considerably totally different from these on the label.

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How is phenylpropanolamine given?

Phenylpropanolamine is given by mouth within the type of a pill or liquid. It could be given with or with out meals; nonetheless, if vomiting happens when dosed on an empty abdomen, give future doses with meals. Measure liquid types rigorously. Present entry to recent water always. If incontinence happens at night time, give the biggest dose at night time, earlier than going to sleep.

This remedy will take impact shortly, in about 1 to 2 hours, and enchancment in scientific indicators ought to comply with.

What if I miss giving my pet the remedy?

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When you miss a dose, give it whenever you keep in mind, however whether it is near the time for the following dose, skip the dose you missed and provides it on the subsequent scheduled time, and return to the common dosing schedule. By no means give your pet two doses without delay or give additional doses.

Are there any potential unwanted effects?

The most typical unwanted effects embrace vomiting, diarrhea, lack of urge for food, elevated thirst, restlessness, irritability, and issue urinating. Critical unwanted effects embrace seizures, collapse, or stroke-like indicators (for instance, not having the ability to stroll).

This short-acting remedy ought to cease working inside 24 hours, though results will be longer in pets with liver or kidney illness.

Are there any danger elements for this remedy?

Phenylpropanolamine shouldn’t be utilized in pets than are allergic to it or in pregnant pets. It must be used cautiously in pets with glaucoma, seizures, enlarged prostate, elevated thyroid hormone, diabetes mellitus, coronary heart or vessel issues, kidney illness, or hypertension. Use phenylpropanolamine cautiously in nursing pets, as security has not been studied.

Are there any drug interactions I ought to pay attention to?

The next drugs must be used with warning when given with phenylpropanolamine: aspirin, isoflurane/desflurane/sevolurane, monoamine oxidase inhibitors (MAOIs), nonsteroidal anti-inflammatory medicine (NSAIDs), reserpine, different sympathomimetics, or tricyclic antidepressants.

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You’ll want to inform your veterinarian about any drugs (together with nutritional vitamins, dietary supplements, or natural therapies) that your pet is taking.

Is there any monitoring that must be executed with this remedy?

Your veterinarian could monitor your pet to ensure that the remedy is working. Monitor your pet at dwelling for severe unwanted effects. Blood stress must be monitored commonly: ceaselessly when your pet first begins taking phenylpropanolamine, after which at the least twice per 12 months.

How do I retailer phenylpropanolamine?

Retailer this remedy at room temperature, and shield from mild and moisture.

What ought to I do in case of emergency?

When you suspect an overdose or an opposed response to the remedy, name your veterinary workplace instantly. If they don’t seem to be accessible, comply with their instructions in contacting an emergency facility.

Contributors: Rania Gollakner, BS, DVM, MPH

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