what is sulfasalazine used for in dogs

what is sulfasalazine used for in dogs

What’s sulfasalazine?

Sulfasalazine (model names: Azulfidine®, Sulfazine®, Salazopyrin®) is a sulfonamide antibacterial and immunosuppressive remedy used to deal with inflammatory massive bowel illness, in addition to for vasculitis in canines.

Its use in cats, canines, ferrets, and horses to deal with inflammatory massive bowel illness or vasculitis is ‘off label’ or ‘additional label’. Many medicine are generally prescribed for off label use in veterinary medication. In these situations, observe your veterinarian’s instructions and cautions very fastidiously as their instructions could also be considerably totally different from these on the label.

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How is sulfasalazine given?

Sulfasalazine is given by mouth within the type of a pill. Give this remedy with meals. Deal with this remedy with warning when you’ve got a identified allergy to sulfa medicine; carrying gloves is beneficial and you should definitely wash your fingers after administering. This remedy ought to take impact inside 1 to 2 hours, and whereas results is probably not visibly apparent, gradual enhancements are often noticeable after a number of days.

What if I miss giving my pet the remedy?

Should you miss a dose, give it if you bear in mind, however whether it is near the time for the subsequent dose, skip the dose you missed and provides it on the subsequent scheduled time, and return to the common dosing schedule. By no means give your pet two doses without delay or give additional doses.

Are there any potential uncomfortable side effects?

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Unwanted effects embrace decreased urge for food, vomiting, yellowing of the pores and skin, eyes, or physique fluids. In cats, lack of urge for food, vomiting, and anemia are attainable. Critical uncomfortable side effects embrace dry eye/keratoconjunctivitis sicca (KCS) which is able to seem as squinting, mucoid eye discharge, and eye discomfort. Different critical uncomfortable side effects embrace lack of vitality, persistent vomiting, diarrhea, lack of urge for food, paleness, fever, and pores and skin rashes.

This short-acting remedy ought to cease working inside 24 hours, though results will be longer in pets with liver or kidney illness.

Are there any danger elements for this remedy?

Sulfasalazine shouldn’t be utilized in pets which can be allergic to it or different sulfonamides or salicylates. It shouldn’t be utilized in Doberman Pinschers, Miniature Schnauzers, or Samoyeds, or in pets with dry eye/KCS, intestinal or urinary blockages, or extreme dehydration.

Sulfasalazine needs to be used cautiously in pets with liver, kidney, or blood illnesses, or in pets which can be pregnant or nursing. Use cautiously in cats, or in delicate canine breeds comparable to Cocker Spaniels, Bulldogs, West Highland Terriers, Lhasa Apsos, or Shih Tzus.

Are there any drug interactions I ought to concentrate on?

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The next medicines needs to be used with warning when given with sulfasalazine: antibacterial brokers, chlorpropamide, cyclosporine, digoxin, ferrous sulfate and different iron salts, folic acid, or warfarin.

Be sure you inform your veterinarian about any medicines (together with nutritional vitamins, dietary supplements, or natural therapies) that your pet is taking.

Is there any monitoring that must be finished with this remedy?

Your veterinarian could monitor your pet to make certain that the remedy is working. Your veterinarian could monitor for KCS/dry eye, by performing a tear check previous to beginning remedy and rechecking frequently throughout remedy. Within the case of long-term remedy, your veterinarian could frequently monitor blood cell counts and liver panels. Monitor your pet at residence for uncomfortable side effects.

How do I retailer sulfasalazine?

Retailer the tablets at room temperature, ideally between 68°F and 77°F (20°C and 25°C); don’t exceed 104°F (40°C). Defend from gentle.

What ought to I do in case of emergency?

Should you suspect an overdose or an opposed response to the remedy, name your veterinary workplace instantly. If they don’t seem to be obtainable, observe their instructions in contacting an emergency facility.

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