what is theophylline used for in dogs

what is theophylline used for in dogs

What’s theophylline?

Theophylline (model names: Theo-24®, Theochron®, Elixophyllin®, Theodur®) is a bronchodilator used to deal with coughs brought on by bronchospasm or bronchoconstriction. It additionally has delicate diuretic results.

Its use in cats and canines to deal with cough and bronchoconstriction is off label’ or further label. Many medication are generally prescribed for off label use in veterinary medication. In these situations, comply with your veterinarian’s instructions and cautions very fastidiously as their instructions could also be considerably totally different from these on the label.

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How is theophylline given?

Theophylline is given by mouth within the type of a pill or liquid, with or with out meals. It could even be administered by your veterinarian in hospital within the type of an injection.

If abdomen upset happens on an empty abdomen, give the remedy with meals. Don’t crush or break the tablets or enable your pet to chew them.

This remedy ought to take impact inside 1 to 2 days, and you need to see enhancements in your pet’s medical indicators.

What if I miss giving my pet the remedy?

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When you miss a dose, give it whenever you bear in mind, however whether it is near the time for the following dose, skip the dose you missed and provides it on the subsequent scheduled time, and return to the common dosing schedule. By no means give your pet two doses directly or give further doses.

Are there any potential unwanted side effects?

The most typical unwanted side effects embody central nervous system stimulation (pleasure) and abdomen or intestinal irritation akin to nausea, vomiting, and diarrhea. Different unwanted side effects embody sleeplessness, elevated consuming, consuming, and urinating.

Extreme poisonous results can happen however are uncommon. These indicators embody seizures and collapse and should point out that the dose of theophylline is just too excessive. Contact your veterinarian instantly should you observe these unwanted side effects in your pet.

This short-acting remedy ought to cease working inside 24 hours, though results may be longer in pets with liver illness or congestive coronary heart failure.

Are there any danger elements for this remedy?

Theophylline shouldn’t be utilized in pets which might be delicate or allergic to it, or associated substances akin to theobromine, aminophylline, or caffeine. It ought to be used with warning in pets with extreme coronary heart illness, irregular coronary heart rhythms, seizures, abdomen ulcers, hyperthyroidism, kidney or liver illness, severely hypertension, or severely low blood oxygen ranges.

It ought to be used with warning in very younger or very previous pets, as poisonous results are extra seemingly. Pets with liver illness or coronary heart failure ought to obtain decrease doses of the remedy. It ought to be used provided that the advantages outweigh the chance in pregnant or nursing pets.

Are there any drug interactions I ought to concentrate on?

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Theophylline ought to be used cautiously with the next drugs, as these drugs can enhance or lower the results of theophylline: barbiturates, carbamazepine, activated charcoal, hydantoins, isoniazid, ketoconazole, loop diuretics, rifampin, sympathomimetics, allopurinol, beta-blockers, calcium channel blockers, cimetidine, corticosteroids, fluoroquinolones, macrolides, mexiletine, thiabendazole, and thyroid hormones.

Theophylline can alter the results of the next drugs, and ought to be used with warning: benzodiazepines, ephedrine, isoproterenol, ketamine, lithium, macrolides, pancuronium, and propofol.

Make sure you inform your veterinarian about any drugs (together with nutritional vitamins, dietary supplements, or natural therapies) that your pet is taking.

Is there any monitoring that must be achieved with this remedy?

Your pet ought to be monitored for indicators of toxicity. Your veterinarian might monitor your pet to make certain that the remedy is working. In some instances, blood ranges of the remedy could also be monitored to make certain the dose is right.

How do I retailer theophylline?

Theophylline tablets or oral liquid ought to be saved at room temperature, under 30°C (86°F), in a tightly closed container.

What ought to I do in case of emergency?

When you suspect an overdose or an antagonistic response to the remedy, name your veterinary workplace instantly. If they aren’t out there, comply with their instructions in contacting an emergency facility.

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